WISP1 抗体
Quick Overview for WISP1 抗体 (ABIN7232144)
抗原
See all WISP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WISP1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of WISP1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human WISP1 protein
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亚型
- IgG
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anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibody
Verified WISP1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 213-350) antibodyWISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 130-251) antibodyWISP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 1-280) antibodyWISP1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 237-295) antibodyWISP1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 171-200) antibodyWISP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2115-2116 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
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别名
- WISP1
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背景
- Rabbit Anti-WISP1 Polyclonal Antibody,WNT1-inducible-signaling pathway protein 1, WISP-1, CCN family member 4, Wnt-1-induced secreted protein,WISP1 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83 % identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.,WISP1
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分子量
- observerd band 40kDa
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基因ID
- 8840
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UniProt
- O95388
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途径
- WNT signaling, Growth Factor Binding
抗原
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