WNK4 抗体
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北京 101111
Quick Overview for WNK4 抗体 (ABIN7232152)
抗原
See all WNK4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-WNK4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of WNK4 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human WNK4 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
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别名
- WNK4
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背景
- Serine/threonine-protein kinase WNK4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4WNK4 (WNK Lysine Deficient Protein Kinase 4) encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in WNK4 result in pseudohypoaldosteronism type IIB.
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分子量
- 136kD
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基因ID
- 65266
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UniProt
- Q96J92
抗原
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