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Vitamin D Receptor 抗体 (pSer51)

This anti-Vitamin D Receptor antibody is a 兔 多克隆 antibody detecting Vitamin D Receptor in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7224898
发货至: 中国

Quick Overview for Vitamin D Receptor 抗体 (pSer51) (ABIN7224898)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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人, 小鼠, 大鼠

宿主

  • 112
  • 11
  • 1
  • 1

克隆类型

  • 95
  • 30
多克隆

标记

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  • 1
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This Vitamin D Receptor antibody is un-conjugated

应用范围

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  • 15
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  • 7
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  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    • 4
    • 3
    • 3
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    pSer51

    原理

    VDR (phospho Ser51) Polyclonal Antibody

    特异性

    Phospho-VDR (S51) Polyclonal Antibody detects endogenous levels of VDR protein only when phosphorylated at S51.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human VDR Phospho-Ser51

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    VDR

    物质类

    Chemical

    背景

    Rabbit Anti-VDR (phospho Ser51) Polyclonal Antibody,VDR, NR1I1, Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1,VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor) encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in VDR are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.,Vitamin D3 receptor

    分子量

    observerd band 38kDa

    基因ID

    7421

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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