VAV1 抗体 (pTyr174)
Quick Overview for VAV1 抗体 (pTyr174) (ABIN7224884)
抗原
See all VAV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr174
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原理
- Vav1 (phospho Tyr174) Polyclonal Antibody
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特异性
- Phospho-Vav1 (Y174) Polyclonal Antibody detects endogenous levels of Vav1 protein only when phosphorylated at Y174.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Vav1 Phospho-Tyr174
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亚型
- IgG
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anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody
VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 565-795) antibodyVAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (pTyr174) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (N-Term) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Vav 1 Oncogene (VAV1) (Center) antibodyVAV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (Tyr174) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 100-200) antibodyVAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (Tyr174) antibodyVAV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- VAV1 (Vav 1 Oncogene (VAV1))
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别名
- Vav1
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背景
- Rabbit Anti-Vav1 (phospho Tyr174) Polyclonal Antibody,VAV1, VAV, Proto-oncogene vav,VAV1 (vav guanine nucleotide exchange factor 1) is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for VAV1.,Proto-oncogene vav
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分子量
- observerd band 98kDa
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基因ID
- 7409
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UniProt
- P15498
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
抗原
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