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VRK1 抗体

This 兔 多克隆 anti-VRK1 antibody specifically detects VRK1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7232118
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VRK1 抗体 (ABIN7232118)

抗原

See all VRK1 抗体
VRK1 (Vaccinia Related Kinase 1 (VRK1))

适用

  • 49
  • 10
  • 3
人, 小鼠

宿主

  • 41
  • 8

克隆类型

  • 43
  • 6
多克隆

标记

  • 24
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VRK1 antibody is un-conjugated

应用范围

  • 41
  • 15
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    VRK1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of VRK1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human VRK1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    别名

    VRK1

    背景

    Rabbit Anti-VRK1 Polyclonal Antibody,Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1,VRK1 encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. VRK1 is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. VRK1, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.,VRK1

    分子量

    observerd band 43kDa

    基因ID

    7443

    UniProt

    Q99986
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