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RENT1/UPF1 抗体 (AA 270-350)

This 兔 多克隆 anti-RENT1/UPF1 antibody specifically detects RENT1/UPF1 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7223988
发货至: 中国
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Quick Overview for RENT1/UPF1 抗体 (AA 270-350) (ABIN7223988)

抗原

See all RENT1/UPF1 (UPF1) 抗体
RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

适用

  • 65
  • 25
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 59
  • 4
  • 3

克隆类型

  • 49
  • 17
多克隆

标记

  • 33
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RENT1/UPF1 antibody is un-conjugated

应用范围

  • 37
  • 21
  • 19
  • 16
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  • 15
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  • 14
  • 12
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-350

    原理

    Rent1 Polyclonal Antibody

    特异性

    Rent1 Polyclonal Antibody detects endogenous levels of Rent1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Rent1 at AA range: 270-350

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

    别名

    Rent1

    背景

    Rabbit Anti-Rent1 Polyclonal Antibody,UPF1, KIAA0221, RENT1, Regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1, NORF1, Up-frameshift suppressor 1 homolog, hUpf1,UPF1 (UPF1, RNA helicase and ATPase) encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for UPF1. Alternative splicing results in multiple transcript variants.,Regulator of nonsense transcripts 1

    分子量

    observerd band 110kDa

    基因ID

    5976

    UniProt

    Q92900

    途径

    SARS-CoV-2 Protein Interactome
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