RENT1/UPF1 抗体 (AA 270-350)
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Quick Overview for RENT1/UPF1 抗体 (AA 270-350) (ABIN7223988)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-350
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原理
- Rent1 Polyclonal Antibody
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特异性
- Rent1 Polyclonal Antibody detects endogenous levels of Rent1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Rent1 at AA range: 270-350
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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别名
- Rent1
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背景
- Rabbit Anti-Rent1 Polyclonal Antibody,UPF1, KIAA0221, RENT1, Regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1, NORF1, Up-frameshift suppressor 1 homolog, hUpf1,UPF1 (UPF1, RNA helicase and ATPase) encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for UPF1. Alternative splicing results in multiple transcript variants.,Regulator of nonsense transcripts 1
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分子量
- observerd band 110kDa
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基因ID
- 5976
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UniProt
- Q92900
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途径
- SARS-CoV-2 Protein Interactome
抗原
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