ULBP2 抗体
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北京 101111
Quick Overview for ULBP2 抗体 (ABIN7229878)
抗原
See all ULBP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- N2DL2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of N2DL2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human N2DL2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ULBP2 (UL16 Binding Protein 2 (ULBP2))
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别名
- N2DL2
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背景
- Rabbit Anti-N2DL2 Polyclonal Antibody,UL16-binding protein 2, ALCAN-alpha, NKG2D ligand 2, N2DL-2, NKG2DL2, Retinoic acid early transcript 1H,ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. ULBP2 is located in a cluster of multiple MHC class I-related genes on chromosome 6. ULBP2 (UL16 Binding Protein 2) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and p53 Pathway (RnD).,N2DL2
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分子量
- observerd band 27kDa
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基因ID
- 80328
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UniProt
- Q9BZM5
抗原
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