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USP37 抗体

The 兔 多克隆 anti-USP37 antibody is suitable to detect USP37 in samples from 人. It has been validated for ELISA 和 WB.
产品编号 ABIN7232016
发货至: 中国
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Quick Overview for USP37 抗体 (ABIN7232016)

抗原

See all USP37 抗体
USP37 (Ubiquitin Specific Peptidase 37 (USP37))

适用

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宿主

  • 32

克隆类型

  • 32
多克隆

标记

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This USP37 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 原理

    UBP37 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of UBP37 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human UBP37 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    USP37 (Ubiquitin Specific Peptidase 37 (USP37))

    别名

    UBP37

    背景

    Rabbit Anti-UBP37 Polyclonal Antibody,Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37,USP37 (Ubiquitin Specific Peptidase 37) is a Protein Coding gene. Among its related pathways are Deubiquitination and Ubiquitin-Proteasome Dependent Proteolysis. Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of Lys-11-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of Lys-48-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.,UBP37

    分子量

    observerd band 107kDa

    基因ID

    57695

    UniProt

    Q86T82
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