USP37 抗体 (Internal Region)
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- 抗原 See all USP37 抗体
- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP37 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- USP37 Antibody detects endogenous levels of total USP37.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP37, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product USP37 Primary Antibody
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anti-Ubiquitin Specific Peptidase 37 (USP37) antibody
USP37 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 671-797) antibodyUSP37 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) antibodyUSP37 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 791-840) antibodyUSP37 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 斑马鱼, 猴, 小鸡, Pig, 非洲爪蟾, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 150-250) antibodyUSP37 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
- 别名
- USP37 (USP37 产品)
- 别名
- 4932415L06Rik antibody, C330008N13Rik antibody, wu:fi15b04 antibody, wu:fi38d03 antibody, zgc:152882 antibody, zgc:153999 antibody, ubiquitin specific peptidase 37 antibody, USP37 antibody, usp37 antibody, Usp37 antibody
- 背景
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Description: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).
Gene: USP37
- 分子量
- ?120 kDa
- 基因ID
- 57695
- UniProt
- Q86T82
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