USP37 抗体
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北京 101111
Quick Overview for USP37 抗体 (ABIN7232016)
抗原
See all USP37 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-UBP37 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of UBP37 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human UBP37 protein
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 37 (USP37) (Internal Region) antibody
USP37 适用: 人, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (C-Term) antibodyUSP37 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) antibodyUSP37 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (C-Term) antibodyUSP37 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) antibodyUSP37 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 671-797) antibodyUSP37 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 791-840) antibodyUSP37 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 斑马鱼, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 37 (USP37) (AA 125-175) antibodyUSP37 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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别名
- UBP37
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背景
- Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37USP37 (Ubiquitin Specific Peptidase 37) is a Protein Coding gene. Among its related pathways are Deubiquitination and Ubiquitin-Proteasome Dependent Proteolysis. Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of Lys-11-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of Lys-48-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.
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分子量
- 107kD
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基因ID
- 57695
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UniProt
- Q86T82
抗原
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