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UFD1L 抗体

This 兔 多克隆 antibody specifically detects UFD1L in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7232030
发货至: 中国
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Quick Overview for UFD1L 抗体 (ABIN7232030)

抗原

See all UFD1L 抗体
UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

适用

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  • 36
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  • 1
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 5

克隆类型

  • 36
  • 17
多克隆

标记

  • 29
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This UFD1L antibody is un-conjugated

应用范围

  • 49
  • 17
  • 15
  • 13
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  • 11
  • 10
  • 6
  • 5
  • 1
Western Blotting (WB), ELISA
  • 原理

    UFD1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of UFD1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human UFD1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

    别名

    UFD1

    背景

    Rabbit Anti-UFD1 Polyclonal Antibody,Ubiquitin recognition factor in ER-associated degradation protein 1, Ubiquitin fusion degradation protein 1, UB fusion protein 1,UFD1 (Ubiquitin Recognition Factor In ER Associated Degradation 1) is a Protein Coding gene. Diseases associated with UFD1 include Velocardiofacial Syndrome and Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia. Among its related pathways are Protein processing in endoplasmic reticulum and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. The protein encoded by UFD1 forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in UFD1 have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.,UFD1

    分子量

    observerd band 33kDa

    基因ID

    7353

    UniProt

    Q92890
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