TIE1 抗体 (AA 820-900)
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Quick Overview for TIE1 抗体 (AA 820-900) (ABIN7224704)
抗原
See all TIE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 820-900
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原理
- Tie-1 Polyclonal Antibody
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特异性
- Tie-1 Polyclonal Antibody detects endogenous levels of Tie-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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别名
- Tie-1
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背景
- Rabbit Anti-Tie-1 Polyclonal Antibody,TIE1, TIE, Tyrosine-protein kinase receptor Tie-1,TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TIE1.,Tyrosine-protein kinase receptor Tie-1
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分子量
- observerd band 130kDa
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基因ID
- 7075
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UniProt
- P35590
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途径
- RTK signaling
抗原
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