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TYK2 抗体

This 兔 多克隆 anti-TYK2 antibody specifically detects TYK2 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 猴 samples.
产品编号 ABIN7217414
发货至: 中国
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Quick Overview for TYK2 抗体 (ABIN7217414)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

  • 85
  • 34
  • 28
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 猴

宿主

  • 73
  • 12

克隆类型

  • 73
  • 13
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
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This TYK2 antibody is un-conjugated

应用范围

  • 66
  • 33
  • 17
  • 14
  • 13
  • 13
  • 9
  • 8
  • 5
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  • 2
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    Tyk 2 Polyclonal Antibody

    特异性

    Tyk 2 Polyclonal Antibody detects endogenous levels of Tyk 2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Tyk 2 around the non-phosphorylation site of Y1054

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    Tyk 2

    背景

    Rabbit Anti-Tyk 2 Polyclonal Antibody,TYK2, Non-receptor tyrosine-protein kinase TYK2,TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,Non-receptor tyrosine-protein kinase TYK2

    分子量

    observerd band 134kDa

    基因ID

    7297

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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