TYK2 抗体
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北京 101111
Quick Overview for TYK2 抗体 (ABIN7217414)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Tyk 2 Polyclonal Antibody
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特异性
- Tyk 2 Polyclonal Antibody detects endogenous levels of Tyk 2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Tyk 2 around the non-phosphorylation site of Y1054
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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别名
- Tyk 2
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背景
- Rabbit Anti-Tyk 2 Polyclonal Antibody,TYK2, Non-receptor tyrosine-protein kinase TYK2,TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,Non-receptor tyrosine-protein kinase TYK2
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分子量
- observerd band 134kDa
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基因ID
- 7297
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UniProt
- P29597
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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