Tropomyosin 抗体 (N-Term)
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Quick Overview for Tropomyosin 抗体 (N-Term) (ABIN7217388)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Tropomyosin α Polyclonal Antibody
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特异性
- Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Tropomyosin alpha
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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别名
- Tropomyosin alpha
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背景
- Rabbit Anti-Tropomyosin α Polyclonal Antibody,TPM1, C15orf13, TMSA, Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1,TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The tropomyosin alpha-1 chain is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.,Tropomyosin alpha-1 chain
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分子量
- observerd band 35kDa
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基因ID
- 7168
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UniProt
- P09493
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途径
- Regulation of Actin Filament Polymerization
抗原
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