TFF1 抗体
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Quick Overview for TFF1 抗体 (ABIN7212348)
抗原
See all TFF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HP-1α Mouse Monoclonal Antibody (5E3)
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特异性
- The antibody detects endogenous HP-1α protein.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Recombinant Protein of HP-1alpha
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亚型
- IgG1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:50-1:2000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TFF1 (Trefoil Factor 1 (TFF1))
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别名
- HP-1alpha
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背景
- Mouse Anti-HP-1α Mouse Monoclonal Antibody (5E3),Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha,CBX5 (chromobox 5) encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. CBX5 has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.,Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
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分子量
- observerd band 22kDa
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基因ID
- 23468
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UniProt
- P45973
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途径
- EGFR Signaling Pathway
抗原
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