STING/TMEM173 抗体 (C-Term)
Quick Overview for STING/TMEM173 抗体 (C-Term) (ABIN7218494)
抗原
See all STING/TMEM173 (TMEM173) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TMEM173 Polyclonal Antibody
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特异性
- TMEM173 Polyclonal Antibody detects endogenous levels of TMEM173 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human TMEM173
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- TMEM173
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背景
- Rabbit Anti-TMEM173 Polyclonal Antibody,TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING,TMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.,Transmembrane protein 173
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分子量
- observerd band 42,23kDa
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基因ID
- 340061
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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