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STING/TMEM173 抗体 (C-Term)

This anti-STING/TMEM173 antibody is a 兔 多克隆 antibody detecting STING/TMEM173 in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7218494
发货至: 中国

Quick Overview for STING/TMEM173 抗体 (C-Term) (ABIN7218494)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

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人, 小鼠

宿主

  • 106
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克隆类型

  • 71
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多克隆

标记

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This STING/TMEM173 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    原理

    TMEM173 Polyclonal Antibody

    特异性

    TMEM173 Polyclonal Antibody detects endogenous levels of TMEM173 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human TMEM173

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    Rabbit Anti-TMEM173 Polyclonal Antibody,TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING,TMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.,Transmembrane protein 173

    分子量

    observerd band 42,23kDa

    基因ID

    340061

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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