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TLR4 抗体 (Internal Region)

This anti-TLR4 antibody is a 兔 多克隆 antibody detecting TLR4 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7214056
发货至: 中国

Quick Overview for TLR4 抗体 (Internal Region) (ABIN7214056)

抗原

See all TLR4 抗体
TLR4 (Toll-Like Receptor 4 (TLR4))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TLR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    原理

    CD284 Polyclonal Antibody

    特异性

    CD284 Polyclonal Antibody detects endogenous levels of CD284 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human CD284

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TLR4 (Toll-Like Receptor 4 (TLR4))

    别名

    CD284

    背景

    Rabbit Anti-CD284 Polyclonal Antibody,TLR4, Toll-like receptor 4, hToll, CD antigen CD284,The protein (toll like receptor 4) encoded by TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in TLR4 have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for TLR4.,Toll-like receptor 4

    分子量

    observerd band 95kDa

    基因ID

    7099

    UniProt

    O00206

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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