TIRAP 抗体
Our Local Distributor
北京 101111
Quick Overview for TIRAP 抗体 (ABIN7219330)
抗原
See all TIRAP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- TIRAP Polyclonal Antibody
-
特异性
- TIRAP Polyclonal Antibody detects endogenous levels of TIRAP protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human TIRAP around the non-phosphorylation site of Y86
-
亚型
- IgG
-
-
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibody
TIRAP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibodyTIRAP 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibodyTIRAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) antibodyTIRAP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-256) antibodyTIRAP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) antibodyTIRAP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2500 unconjugated Recombinant Antibody
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (N-Term) antibodyTIRAP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
-
别名
- TIRAP
-
背景
- Rabbit Anti-TIRAP Polyclonal Antibody,TIRAP, MAL, Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein,The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.,Toll interleukin-1 receptor domain-containing adapter protein
-
基因ID
- 114609
-
UniProt
- P58753
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
-
