KLF10/11 抗体 (AA 360-440)
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Quick Overview for KLF10/11 抗体 (AA 360-440) (ABIN7224702)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 360-440
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原理
- Rabbit Anti-TIEG-1/2 Polyclonal Antibody
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特异性
- TIEG-1/2 Polyclonal Antibody detects endogenous levels of TIEG-1/2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human TIEG-1/2 at AA range: 360-440
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- KLF10/11 (Kruppel-Like Factor 10/11 (KLF10/11))
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别名
- TIEG-1/2
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背景
- KLF10, TIEG, TIEG1, Krueppel-like factor 10, EGR-alpha, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1, KLF11, FKLF, TIEG2, Krueppel-like factor 11, TransforKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.
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基因ID
- 7071, 8462
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UniProt
- Q13118, O14901
抗原
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