TEK 抗体 (pTyr1108)
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北京 101111
Quick Overview for TEK 抗体 (pTyr1108) (ABIN7224648)
抗原
See all TEK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1108
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原理
- Tie-2 (phospho Tyr1108) Polyclonal Antibody
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特异性
- Phospho-Tie-2 (Y1108) Polyclonal Antibody detects endogenous levels of Tie-2 protein only when phosphorylated at Y1108.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Tie-2 Phospho-Tyr1108
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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别名
- Tie-2
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背景
- Rabbit Anti-Tie-2 (phospho Tyr1108) Polyclonal Antibody,TEK, TIE2, VMCM, VMCM1, Angiopoietin-1 receptor, Endothelial tyrosine kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor,TEK (TEK receptor tyrosine kinase) encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in TEK are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of TEK have been described, but their full-length nature is not known.,Angiopoietin-1 receptor
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分子量
- observerd band 150kDa
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基因ID
- 7010
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UniProt
- Q02763
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途径
- RTK signaling, Growth Factor Binding
抗原
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