TBK1 抗体
Quick Overview for TBK1 抗体 (ABIN7221362)
抗原
See all TBK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TBK1 Polyclonal Antibody
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特异性
- TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human TBK1 around the non-phosphorylation site of S172
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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别名
- TBK1
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背景
- Rabbit Anti-TBK1 Polyclonal Antibody,TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1,The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The TANK binding kinase 1 encoded by TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.,serine threonine-protein kinase TBK1
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基因ID
- 29110
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UniProt
- Q9UHD2
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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