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TBK1 抗体

This anti-TBK1 antibody is a 兔 多克隆 antibody detecting TBK1 in ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7221362
发货至: 中国

Quick Overview for TBK1 抗体 (ABIN7221362)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

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  • 2
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  • 1
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人, 小鼠

宿主

  • 91
  • 3
  • 1

克隆类型

  • 70
  • 25
多克隆

标记

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This TBK1 antibody is un-conjugated

应用范围

  • 72
  • 45
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  • 19
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  • 9
  • 8
  • 7
  • 2
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  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    TBK1 Polyclonal Antibody

    特异性

    TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human TBK1 around the non-phosphorylation site of S172

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    TBK1

    背景

    Rabbit Anti-TBK1 Polyclonal Antibody,TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1,The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The TANK binding kinase 1 encoded by TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.,serine threonine-protein kinase TBK1

    基因ID

    29110

    UniProt

    Q9UHD2

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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