SNAP23 抗体 (C-Term)
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Quick Overview for SNAP23 抗体 (C-Term) (ABIN7217998)
抗原
See all SNAP23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SNAP 23 Polyclonal Antibody
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特异性
- SNAP 23 Polyclonal Antibody detects endogenous levels of SNAP 23 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human SNAP 23
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
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别名
- SNAP 23
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背景
- Rabbit Anti-SNAP 23 Polyclonal Antibody,SNAP23, Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23,Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.,Synaptosomal-associated protein 23
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分子量
- observerd band 25kDa
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基因ID
- 8773
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UniProt
- O00161
抗原
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