SREBF1 抗体 (pSer439)
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北京 101111
Quick Overview for SREBF1 抗体 (pSer439) (ABIN7224464)
抗原
See all SREBF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer439
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原理
- SREBP-1 (phospho Ser439) Polyclonal Antibody
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特异性
- Phospho-SREBP-1 (S439) Polyclonal Antibody detects endogenous levels of SREBP-1 protein only when phosphorylated at S439.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human SREBP-1 Phospho-Ser439
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亚型
- IgG
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anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 38-201) antibody
SREBF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 801-900) antibodySREBF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 1-100) antibodySREBF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (pSer439) antibodySREBF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 349-378) antibodySREBF1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21265 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 适用: 人, 大鼠, 小鼠, Cow, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 158-390) antibodySREBF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 461-510) antibodySREBF1 适用: 人, 大鼠, Cow, 山羊, 马, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 适用: 人, 大鼠, 小鼠, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) antibodySREBF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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别名
- SREBP-1
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背景
- Rabbit Anti-SREBP-1 (phospho Ser439) Polyclonal Antibody,SREBF1, BHLHD1, SREBP1, Sterol regulatory element-binding protein 1, SREBP-1, Class D basic helix-loop-helix protein 1, bHLHd1, Sterol regulatory element-binding transcription factor 1,SREBF1 (sterol regulatory element binding transcription factor 1) encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. SREBF1 is located within the Smith-Magenis syndrome region on chromosome 17.,Sterol regulatory element-binding protein 1
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分子量
- observerd band 122kDa
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基因ID
- 6720
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UniProt
- P36956
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途径
- AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
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