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SP1 抗体 (pThr453)

This anti-SP1 antibody is a 兔 多克隆 antibody detecting SP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7224432
发货至: 中国

Quick Overview for SP1 抗体 (pThr453) (ABIN7224432)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pThr453

    原理

    Sp1 (phospho Thr453) Polyclonal Antibody

    特异性

    Phospho-Sp1 (T453) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T453.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Sp1 Phospho-Thr453

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    别名

    Sp1

    背景

    Rabbit Anti-Sp1 (phospho Thr453) Polyclonal Antibody,SP1, TSFP1, Transcription factor Sp1,The protein encoded by SP1 (Sp1 transcription factor) is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for SP1.,Transcription factor Sp1

    分子量

    observerd band 90kDa

    基因ID

    6667

    UniProt

    P08047

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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