SMAD3 抗体 (pSer213)
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Quick Overview for SMAD3 抗体 (pSer213) (ABIN7231398)
抗原
See all SMAD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer213
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原理
- Smad3 (Phospho-Ser213) Polyclonal Antibody
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特异性
- This antibody detects endogenous levels of Smad3 when Phospho occurs at Ser213
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human Smad3 (Phospho-Ser213) Antibody protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
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别名
- Smad3
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背景
- Rabbit Anti-Smad3 (Phospho-Ser213) Polyclonal Antibody,Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3,SMAD3 (SMAD Family Member 3) is a Protein Coding gene. Diseases associated with SMAD3 include Loeys-Dietz Syndrome 3 and Smad3-Related Loeys-Dietz Syndrome. Among its related pathways are Transcription Androgen Receptor nuclear signaling and AGE/RAGE pathway. The protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene' mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.,Smad3
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分子量
- observerd band 50kDa
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基因ID
- 4088
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UniProt
- P84022
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途径
- Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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