SKIL 抗体 (AA 590-670)
Quick Overview for SKIL 抗体 (AA 590-670) (ABIN7217066)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 590-670
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原理
- SnoN Polyclonal Antibody
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特异性
- SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human SnoN at AA range: 590-670
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SKIL (SKI-Like Oncogene (SKIL))
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别名
- SnoN
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背景
- Rabbit Anti-SnoN Polyclonal Antibody,SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein,Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,Ski-like protein
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分子量
- observerd band 77kDa
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基因ID
- 6498
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UniProt
- P12757
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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