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SKIL 抗体 (AA 590-670)

This anti-SKIL antibody is a 兔 多克隆 antibody detecting SKIL in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7217066
发货至: 中国

Quick Overview for SKIL 抗体 (AA 590-670) (ABIN7217066)

抗原

See all SKIL 抗体
SKIL (SKI-Like Oncogene (SKIL))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SKIL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 590-670

    原理

    SnoN Polyclonal Antibody

    特异性

    SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human SnoN at AA range: 590-670

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SKIL (SKI-Like Oncogene (SKIL))

    别名

    SnoN

    背景

    Rabbit Anti-SnoN Polyclonal Antibody,SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein,Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,Ski-like protein

    分子量

    observerd band 77kDa

    基因ID

    6498

    UniProt

    P12757

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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