STAT4 抗体 (pTyr693)
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Quick Overview for STAT4 抗体 (pTyr693) (ABIN7213124)
抗原
See all STAT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr693
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原理
- Stat4 (phospho Tyr693) Polyclonal Antibody
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特异性
- Phospho-Stat4 (Y693) Polyclonal Antibody detects endogenous levels of Stat4 protein only when phosphorylated at Y693.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Stat4 Phospho-Tyr693
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 μg/mg lysate), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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别名
- Stat4
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背景
- Rabbit Anti-Stat4 (phospho Tyr693) Polyclonal Antibody,STAT4, Signal transducer and activator of transcription 4,Signal transducer and activator of transcription 4 encoded by STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Signal transducer and activator of transcription 4 is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in STAT4 may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.,Signal transducer and activator of transcription 4
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分子量
- observerd band 86kDa
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基因ID
- 6775
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UniProt
- Q14765
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途径
- JAK/STAT Signaling
抗原
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