STAT1 抗体
Quick Overview for STAT1 抗体 (ABIN7212170)
抗原
See all STAT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STAT1 Mouse Monoclonal Antibody (8H11)
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特异性
- STAT1 protein detects endogenous levels of STAT1.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Synthetic Peptide of STAT1 at AA range of 640-720
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亚型
- IgG1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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别名
- STAT1
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背景
- Mouse Anti-STAT1 Mouse Monoclonal Antibody (8H11),STAT1,The protein encoded by STAT1 (signal transducer and activator of transcription 1) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.,STAT1
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分子量
- observerd band 84,91kDa
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基因ID
- 6772
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UniProt
- P42224
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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