SKP1 抗体 (AA 10-90)
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Quick Overview for SKP1 抗体 (AA 10-90) (ABIN7217022)
抗原
See all SKP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Skp1 p19 Polyclonal Antibody
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特异性
- Skp1 p19 Polyclonal Antibody detects endogenous levels of Skp1 p19 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Skp1 p19 at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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别名
- Skp1 p19
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背景
- Rabbit Anti-Skp1 p19 Polyclonal Antibody,SKP1, EMC19, OCP2, SKP1A, TCEB1L, S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, Organ of Corti protein 2, OCP-2, Organ of Corti protein II, OCP-II, RNA polymerase II elongation factor-like protein, SIII, Transcr,SKP1 encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. S-phase kinase-associated protein 1 binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.,S-phase kinase-associated protein 1
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分子量
- observerd band 19kDa
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基因ID
- 6500
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UniProt
- P63208
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
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