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POLR2A/RPB1 抗体 (pSer1619)

This anti-POLR2A/RPB1 antibody is a 兔 多克隆 antibody detecting POLR2A/RPB1 in WB, IF, ELISA 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7223258
发货至: 中国
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Quick Overview for POLR2A/RPB1 抗体 (pSer1619) (ABIN7223258)

抗原

See all POLR2A/RPB1 (POLR2A) 抗体
POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 94
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克隆类型

  • 66
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多克隆

标记

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This POLR2A/RPB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer1619

    原理

    Rpb1 (phospho Ser1619) Polyclonal Antibody

    特异性

    Phospho-Rpb1 (S1619) Polyclonal Antibody detects endogenous levels of Rpb1 protein only when phosphorylated at S1619.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Rpb1 Phospho-Ser1619

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

    别名

    Rpb1

    背景

    Rabbit Anti-Rpb1 (phospho Ser1619) Polyclonal Antibody,POLR2A, POLR2, DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1,POLR2A (RNA polymerase II subunit A) encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of POLR2A contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.,DNA-directed RNA polymerase II subunit RPB1

    分子量

    observerd band 250kDa

    基因ID

    5430

    UniProt

    P24928

    途径

    Regulatory RNA Pathways
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