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RNF111 抗体 (AA 870-950)

The 兔 多克隆 anti-RNF111 antibody is suitable to detect RNF111 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7223318
发货至: 中国
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Quick Overview for RNF111 抗体 (AA 870-950) (ABIN7223318)

抗原

See all RNF111 抗体
RNF111 (Ring Finger Protein 111 (RNF111))

适用

  • 34
  • 32
  • 23
人, 小鼠

宿主

  • 45
  • 4

克隆类型

  • 47
  • 2
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF111 antibody is un-conjugated

应用范围

  • 20
  • 18
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 870-950

    原理

    Arkadia Polyclonal Antibody

    特异性

    Arkadia Polyclonal Antibody detects endogenous levels of Arkadia protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Arkadia at AA range: 870-950

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RNF111 (Ring Finger Protein 111 (RNF111))

    别名

    Arkadia

    背景

    Rabbit Anti-Arkadia Polyclonal Antibody,RNF111, E3 ubiquitin-protein ligase Arkadia, RING finger protein 111,The protein encoded by RNF111 (ring finger protein 111) is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF)-beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, RNF111 plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of RNF111 results in multiple transcript variants encoding distinct isoforms.,E3 ubiquitin-protein ligase Arkadia

    基因ID

    54778

    UniProt

    Q6ZNA4
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