RPSA/Laminin Receptor 抗体 (Internal Region)
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Quick Overview for RPSA/Laminin Receptor 抗体 (Internal Region) (ABIN7222166)
抗原
See all RPSA/Laminin Receptor (RPSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Laminin-R Polyclonal Antibody
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特异性
- Laminin-R Polyclonal Antibody detects endogenous levels of Laminin-R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Laminin-R
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亚型
- IgG
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anti-Ribosomal Protein SA (RPSA) antibody
RPSA 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal RPSA-2699 unconjugated
anti-Ribosomal Protein SA (RPSA) (AA 1-295) antibodyRPSA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein SA (RPSA) antibodyRPSA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein SA (RPSA) (AA 101-200) antibodyRPSA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein SA (RPSA) (AA 107-156) antibodyRPSA 适用: 人, 小鼠, 大鼠, Pig, Cow, 绵羊, 小鸡, 犬, 山羊, 马, 兔, 斑马鱼, 豚鼠, 非洲爪蟾, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein SA (RPSA) antibodyKO Validated RPSA 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2950 unconjugated Recombinant Antibody
anti-Ribosomal Protein SA (RPSA) (AA 196-295) antibodyRPSA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G4 unconjugated
anti-Ribosomal Protein SA (RPSA) (N-Term) antibodyRPSA 适用: 人, 小鼠, 大鼠, Pig, Cow, 绵羊, 小鸡, 犬, 山羊, 马, 兔, 豚鼠, 非洲爪蟾, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein SA (RPSA) antibodyRPSA 适用: 人, 小鼠, Cow, 小鸡, 非洲爪蟾 WB, ELISA, IHC (p), IP, ICC, ICFC 宿主: 小鼠 Monoclonal RP-01 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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别名
- Laminin-R
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背景
- Rabbit Anti-Laminin-R Polyclonal Antibody,RPSA, LAMBR, LAMR1, 40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin-binding protein, Laminin receptor 1, LamR, Laminin-binding pr,Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. RPSA encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of RPSA exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.,40S ribosomal protein SA
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分子量
- observerd band 43kDa
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基因ID
- 3921
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UniProt
- P08865
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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