ARHGEF3 抗体 (AA 430-510)
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北京 101111
Quick Overview for ARHGEF3 抗体 (AA 430-510) (ABIN7217518)
抗原
See all ARHGEF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 430-510
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原理
- XPLN Polyclonal Antibody
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特异性
- XPLN Polyclonal Antibody detects endogenous levels of XPLN protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human XPLN at AA range: 430-510
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibody
ARHGEF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 33-142) antibodyARHGEF3 适用: 人 ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) antibodyARHGEF3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 211-240) antibodyARHGEF3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27451 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibodyARHGEF3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 1-324) antibodyARHGEF3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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别名
- XPLN
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背景
- Rabbit Anti-XPLN Polyclonal Antibody,ARHGEF3, Rho guanine nucleotide exchange factor 3, Exchange factor found in platelets and leukemic and neuronal tissues, XPLN,Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. ARHGEF3 encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: rHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Rho guanine nucleotide exchange factor 3
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分子量
- observerd band 55kDa
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基因ID
- 50650
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UniProt
- Q9NR81
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途径
- Neurotrophin Signaling Pathway
抗原
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