ARHGAP11A 抗体 (AA 440-520)
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北京 101111
Quick Overview for ARHGAP11A 抗体 (AA 440-520) (ABIN7226098)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 440-520
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原理
- ARHGAP11A Polyclonal Antibody
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特异性
- ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human ARHGAP11A at AA range: 440-520
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亚型
- IgG
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anti-rho GTPase Activating Protein 11A (ARHGAP11A) antibody
ARHGAP11A 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 11A (ARHGAP11A) (C-Term) antibodyARHGAP11A 适用: 人, 小鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 11A (ARHGAP11A) (N-Term) antibodyARHGAP11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARHGAP11A (rho GTPase Activating Protein 11A (ARHGAP11A))
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别名
- ARHGAP11A
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背景
- Rabbit Anti-ARHGAP11A Polyclonal Antibody,ARHGAP11A, KIAA0013, Rho GTPase-activating protein 11A, Rho-type GTPase-activating protein 11A,GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP11A (Rho GTPase activating protein 11A), also known as KIAA0013 or MGC70740, is a 1,023 amino acid protein that contains one helical Rho-GAP domain and is encoded by a gene located on human chromosome 15. Defects in the gene encoding ARHGAP11A may cause mental retardation. Human chromosome 15 encodes over 700 genes and comprises nearly 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.,Rho GTPase-activating protein 11A
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基因ID
- 9824
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UniProt
- Q6P4F7
抗原
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