ARHGAP11A 抗体 (AA 471-520)
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北京 101111
Quick Overview for ARHGAP11A 抗体 (AA 471-520) (ABIN1451550)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-520
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原理
- ARHGAP11A Antibody
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特异性
- ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ARHGAP11A. AA range:471-520
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ARHGAP11A (rho GTPase Activating Protein 11A (ARHGAP11A))
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别名
- ARHGAP11A
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背景
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Synonyms: ARHGAP11A, KIAA0013, Rho GTPase-activating protein 11A, Rho-type GTPase-activating protein 11A
Background: This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],
Gene Name: ARHGAP11A
Protein Name: Rho GTPase-activating protein 11A
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分子量
- 113 kDa
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基因ID
- 9824
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OMIM
- 610589
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UniProt
- Q6P4F7
抗原
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