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RGR 抗体 (AA 140-220)

This anti-RGR antibody is a 兔 多克隆 antibody detecting RGR in ELISA, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN7224010
发货至: 中国

Quick Overview for RGR 抗体 (AA 140-220) (ABIN7224010)

抗原

See all RGR 抗体
RGR (Retinal G Protein Coupled Receptor (RGR))

适用

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宿主

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克隆类型

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多克隆

标记

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This RGR antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    AA 140-220

    原理

    RGR Polyclonal Antibody

    特异性

    RGR Polyclonal Antibody detects endogenous levels of RGR protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human RGR at AA range: 140-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RGR (Retinal G Protein Coupled Receptor (RGR))

    别名

    RGR

    背景

    Rabbit Anti-RGR Polyclonal Antibody,RGR, RPE-retinal G protein-coupled receptor,RGR (retinal G protein coupled receptor) encodes a putative retinal G-protein coupled receptor. RGR is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.,RPE-retinal G protein-coupled receptor

    基因ID

    5995

    UniProt

    P47804
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