RGR 抗体 (AA 140-220)
Quick Overview for RGR 抗体 (AA 140-220) (ABIN7224010)
抗原
See all RGR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-220
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原理
- RGR Polyclonal Antibody
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特异性
- RGR Polyclonal Antibody detects endogenous levels of RGR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human RGR at AA range: 140-220
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RGR (Retinal G Protein Coupled Receptor (RGR))
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别名
- RGR
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背景
- Rabbit Anti-RGR Polyclonal Antibody,RGR, RPE-retinal G protein-coupled receptor,RGR (retinal G protein coupled receptor) encodes a putative retinal G-protein coupled receptor. RGR is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.,RPE-retinal G protein-coupled receptor
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基因ID
- 5995
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UniProt
- P47804
抗原
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