RTN4RL2 抗体 (AA 290-370)
Quick Overview for RTN4RL2 抗体 (AA 290-370) (ABIN7230866)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-370
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原理
- R4RL2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of R4RL2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human R4RL2 protein at AA range: 290-370
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亚型
- IgG
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anti-Reticulon 4 Receptor-Like 2 (RTN4RL2) (AA 241-337) antibody
RTN4RL2 适用: 人, Cow ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor-Like 2 (RTN4RL2) (AA 355-372) antibodyRTN4RL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor-Like 2 (RTN4RL2) (C-Term) antibodyRTN4RL2 适用: 人 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor-Like 2 (RTN4RL2) (C-Term) antibodyRTN4RL2 适用: 人, 大鼠, 小鼠, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))
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别名
- R4RL2
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背景
- Rabbit Anti-R4RL2 Polyclonal Antibody,Nogo receptor-like 3, Nogo-66 receptor homolog 1, Nogo-66 receptor-related protein 2, NgR2,RTN4RL2 (Reticulon 4 Receptor Like 2) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. GO annotations related to this gene include receptor activity. An important paralog of this gene is RTN4RL1. Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).,R4RL2
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分子量
- observerd band 46kDa
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基因ID
- 349667
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UniProt
- Q86UN3
抗原
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