RIPK3 抗体
Our Local Distributor
北京 101111
Quick Overview for RIPK3 抗体 (ABIN7231068)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-RIPK3 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of RIPK3 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human RIPK3 protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
-
别名
- RIPK3
-
背景
- Receptor-interacting serine/threonine-protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3The product of RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases and contains a C-terminal domain unique from other RIP family members. Receptor Interacting Serine/Threonine Kinase 3 is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
-
分子量
- 56kD
-
基因ID
- 11035
-
UniProt
- Q9Y572
-
途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-