RAD21 抗体 (AA 490-570)
Quick Overview for RAD21 抗体 (AA 490-570) (ABIN7223894)
抗原
See all RAD21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-570
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原理
- Rad21 Polyclonal Antibody
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特异性
- Rad21 Polyclonal Antibody detects endogenous levels of Rad21 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Rad21 at AA range: 490-570
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAD21 (RAD21 Homolog (RAD21))
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别名
- Rad21
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背景
- Rabbit Anti-Rad21 Polyclonal Antibody,RAD21, HR21, KIAA0078, NXP1, Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog,The protein encoded by RAD21 (RAD21 cohesin complex component) is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.,Double-strand-break repair protein rad21 homolog
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分子量
- observerd band 72kDa
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基因ID
- 5885
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UniProt
- O60216
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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