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RACGAP1 抗体 (pSer387)

The 兔 多克隆 anti-RACGAP1 antibody is suitable to detect RACGAP1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN7221368
发货至: 中国
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Quick Overview for RACGAP1 抗体 (pSer387) (ABIN7221368)

抗原

See all RACGAP1 抗体
RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 94
  • 4
  • 1
  • 1

克隆类型

  • 84
  • 16
多克隆

标记

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  • 1
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This RACGAP1 antibody is un-conjugated

应用范围

  • 87
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  • 12
  • 7
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  • 2
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 18
    • 15
    • 8
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    • 5
    • 5
    • 3
    • 2
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    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer387

    原理

    Rac GAP1 (phospho Ser387) Polyclonal Antibody

    特异性

    Phospho-Rac GAP1 (S387) Polyclonal Antibody detects endogenous levels of Rac GAP1 protein only when phosphorylated at S387.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Rac GAP1 Phospho-Ser387

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

    别名

    Rac GAP1

    背景

    Rabbit Anti-Rac GAP1 (phospho Ser387) Polyclonal Antibody,RACGAP1, KIAA1478, MGCRACGAP, Rac GTPase-activating protein 1, Male germ cell RacGap, MgcRacGAP, Protein CYK4 homolg, CYK4, HsCYK-4,RACGAP1 encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.,Rac GTPase-activating protein 1

    分子量

    observerd band 72kDa

    基因ID

    29127

    UniProt

    Q9H0H5

    途径

    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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