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RAB43 抗体 (AA 90-170)

This 兔 多克隆 anti-RAB43 antibody specifically detects RAB43 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7230894
发货至: 中国
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Quick Overview for RAB43 抗体 (AA 90-170) (ABIN7230894)

抗原

See all RAB43 抗体
RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

适用

  • 11
  • 2
  • 1

宿主

  • 8
  • 3

克隆类型

  • 9
  • 2
多克隆

标记

  • 11
This RAB43 antibody is un-conjugated

应用范围

  • 11
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 90-170

    原理

    RAB43 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of RAB43 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human RAB43 protein at AA range: 90-170

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

    别名

    RAB43

    背景

    Rabbit Anti-RAB43 Polyclonal Antibody,Ras-related protein Rab-43, Ras-related protein Rab-41,RAB43 (RAB43, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are RAB geranylgeranylation and Golgi-to-ER retrograde transport. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. ureus and M. uberculosis.,RAB43

    分子量

    observerd band 23kDa

    基因ID

    339122

    UniProt

    Q86YS6
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