RAB43 抗体 (AA 90-170)
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Quick Overview for RAB43 抗体 (AA 90-170) (ABIN7230894)
抗原
See all RAB43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-170
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原理
- RAB43 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RAB43 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human RAB43 protein at AA range: 90-170
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
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别名
- RAB43
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背景
- Rabbit Anti-RAB43 Polyclonal Antibody,Ras-related protein Rab-43, Ras-related protein Rab-41,RAB43 (RAB43, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are RAB geranylgeranylation and Golgi-to-ER retrograde transport. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. ureus and M. uberculosis.,RAB43
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分子量
- observerd band 23kDa
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基因ID
- 339122
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UniProt
- Q86YS6
抗原
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