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RAB43 抗体 (C-Term)

RAB43 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515092
发货至: 中国
  • 抗原 See all RAB43 抗体
    RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 16
    • 2
    • 1
    宿主
    • 13
    • 3
    克隆类型
    • 14
    • 2
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB43 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 2
    • 1
    Western Blotting (WB)
    序列
    ETSAKDSSNV EEAFLRVATE LIMRHGGPLF SEKSPDHIQL NSKDIGEGWG
    产品特性
    This is a rabbit polyclonal antibody against RAB43. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAB43
    Top Product
    Discover our top product RAB43 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
    别名
    RAB43 (RAB43 产品)
    别名
    rab43 antibody, fi21h07 antibody, wu:fi21h07 antibody, zgc:136785 antibody, RAB11B antibody, RAB41 antibody, 1810048P08Rik antibody, 2500004H21Rik antibody, AW490415 antibody, RAB43, member RAS oncogene family antibody, ISY1 splicing factor homolog antibody, RAB43 antibody, rab43 antibody, isy1 antibody, Rab43 antibody
    背景
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. RAB43 is involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. It plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

    Alias Symbols: RAB41

    Protein Size: 212
    基因ID
    339122
    NCBI登录号
    NP_940892
    UniProt
    Q86YS6
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