RAB21 抗体 (AA 60-140)
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北京 101111
Quick Overview for RAB21 抗体 (AA 60-140) (ABIN7230882)
抗原
See all RAB21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-140
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原理
- Rabbit Anti-RAB21 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RAB21 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human RAB21 protein at AA range: 60-140
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- RAB21 (RAB21, Member RAS Oncogene Family (RAB21))
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别名
- RAB21
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背景
- Ras-related protein Rab-21RAB21 (RAB21, Member RAS Oncogene Family) belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of RAB21 is associated with a poor prognosis for glioma patients. RAB21 is downregulated by the tumor suppressor miR-200b and miRNA-200b is itself downregulated in glioma tissues.
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分子量
- 24kD
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基因ID
- 23011
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UniProt
- Q9UL25
抗原
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