PTK2B 抗体
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北京 101111
Quick Overview for PTK2B 抗体 (ABIN7216708)
抗原
See all PTK2B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PYK2 Polyclonal Antibody
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特异性
- PYK2 Polyclonal Antibody detects endogenous levels of PYK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human PYK2 around the non-phosphorylation site of Y580
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亚型
- IgG
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anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 1-1009) antibodyPTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibodyPTK2B 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB1155 unconjugated Recombinant Antibody
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibodyPTK2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibodyPTK2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 805-838), (C-Term) antibodyPTK2B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB50594 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 812-861) antibodyPTK2B 适用: 人, 小鼠, 大鼠, 犬, 兔, 猴, Pig, 马, Cow, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal X1 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 815-997) antibodyPTK2B 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5E2D5 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
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别名
- PYK2
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背景
- Rabbit Anti-PYK2 Polyclonal Antibody,PTK2B, FAK2, PYK2, RAFTK, Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, CADTK, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, CAK-beta, CAKB, Focal adhesion kinase 2, FADK 2, Pro,PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. protein tyrosine kinase 2 beta may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. protein tyrosine kinase 2 beta undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. protein tyrosine kinase 2 beta has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. protein tyrosine kinase 2 beta is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for PTK2B.,Protein-tyrosine kinase 2-beta
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分子量
- observerd band 115kDa
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基因ID
- 2185
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UniProt
- Q14289
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
抗原
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