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PTPN12 抗体

This 兔 多克隆 anti-PTPN12 antibody specifically detects PTPN12 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230828
发货至: 中国
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Quick Overview for PTPN12 抗体 (ABIN7230828)

抗原

See all PTPN12 抗体
PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

适用

  • 57
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  • 1
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人, 小鼠

宿主

  • 52
  • 5

克隆类型

  • 53
  • 4
多克隆

标记

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  • 1
  • 1
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This PTPN12 antibody is un-conjugated

应用范围

  • 45
  • 14
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  • 12
  • 10
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  • 6
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  • 1
Western Blotting (WB), ELISA
  • 原理

    PTN12 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PTN12 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PTN12 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

    别名

    PTN12

    背景

    Rabbit Anti-PTN12 Polyclonal Antibody,Tyrosine-protein phosphatase non-receptor type 12, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1,PTPN12 (Protein Tyrosine Phosphatase, Non-Receptor Type 12) is a Protein Coding gene. Diseases associated with PTPN12 include Colorectal Cancer and Colonic Benign Neoplasm. Among its related pathways are DNA Damage and Signaling by ERBB2. The protein encoded by PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility.,PTN12

    分子量

    observerd band 85kDa

    基因ID

    5782

    UniProt

    Q05209
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