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PKC delta 抗体 (pTyr313)

This anti-PKC delta antibody is a 兔 多克隆 antibody detecting PKC delta in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7223512
发货至: 中国
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Quick Overview for PKC delta 抗体 (pTyr313) (ABIN7223512)

抗原

See all PKC delta (PKCd) 抗体
PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PKC delta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pTyr313

    原理

    PKC δ (phospho Tyr313) Polyclonal Antibody

    特异性

    Phospho-PKC δ (Y313) Polyclonal Antibody detects endogenous levels of PKC δ protein only when phosphorylated at Y313.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PKC delta Phospho-Tyr313

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

    别名

    PKC delta

    背景

    Rabbit Anti-PKC δ (phospho Tyr313) Polyclonal Antibody,PRKCD, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta,Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by PRKCD (protein kinase C delta) is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.,Protein kinase C delta type

    分子量

    observerd band 78kDa

    基因ID

    5580

    UniProt

    Q05655

    途径

    Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
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