PICK1 抗体
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北京 101111
Quick Overview for PICK1 抗体 (ABIN7230634)
抗原
See all PICK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-PICK1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PICK1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human PICK1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
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别名
- PICK1
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背景
- PRKCA-binding protein, Protein interacting with C kinase 1, Protein kinase C-alpha-binding proteinThe protein encoded by PICK1 gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
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分子量
- 45kD
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基因ID
- 9463
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UniProt
- Q9NRD5
抗原
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