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PIAS1 抗体 (AA 10-90)

This 兔 多克隆 anti-PIAS1 antibody specifically detects PIAS1 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7216552
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PIAS1 抗体 (AA 10-90) (ABIN7216552)

抗原

See all PIAS1 抗体
PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

适用

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人, 小鼠

宿主

  • 58
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克隆类型

  • 45
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多克隆

标记

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This PIAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 10-90

    原理

    PIAS 1 Polyclonal Antibody

    特异性

    PIAS 1 Polyclonal Antibody detects endogenous levels of PIAS 1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human PIAS 1 at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

    别名

    PIAS 1

    背景

    Rabbit Anti-PIAS 1 Polyclonal Antibody,PIAS1, DDXBP1, E3 SUMO-protein ligase PIAS1, DEAD/H box-binding protein 1, Gu-binding protein, GBP, Protein inhibitor of activated STAT protein 1, RNA helicase II-binding protein,PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.,E3 SUMO-protein ligase PIAS1

    分子量

    observerd band 72kDa

    基因ID

    8554

    UniProt

    O75925

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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