POLR3G 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for POLR3G 抗体 (Internal Region) (ABIN7218496)
抗原
See all POLR3G 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
原理
- POLR3G Polyclonal Antibody
-
特异性
- POLR3G Polyclonal Antibody detects endogenous levels of POLR3G protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human POLR3G
-
亚型
- IgG
-
-
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (Internal Region) antibody
POLR3G 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (Internal Region) antibodyPOLR3G 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (N-Term) antibodyPOLR3G 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 1-223) antibodyPOLR3G 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 88-137) antibodyPOLR3G 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 195-223), (C-Term) antibodyPOLR3G 适用: 人 WB 宿主: 兔 Polyclonal RB36682 unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- POLR3G (Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))
-
别名
- POLR3G
-
背景
- Rabbit Anti-POLR3G Polyclonal Antibody,POLR3G, DNA-directed RNA polymerase III subunit RPC7, RNA polymerase III subunit C7, DNA-directed RNA polymerase III subunit G, RNA polymerase III 32 kDa subunit, RPC32,DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.,DNA-directed RNA polymerase III subunit RPC7
-
分子量
- observerd band 26kDa
-
基因ID
- 10622
-
UniProt
- O15318
抗原
-
