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- 抗原 See all POLR3G 抗体
- POLR3G (Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3G antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- RPC7 Antibody detects endogenous levels of total RPC7.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RPC7, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product POLR3G Primary Antibody
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (Internal Region) antibody
POLR3G 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (Internal Region) antibodyPOLR3G 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 1-223) antibodyPOLR3G 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 88-137) antibodyPOLR3G 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G) (AA 195-223), (C-Term) antibodyPOLR3G 适用: 人 WB 宿主: 兔 Polyclonal RB36682 unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- POLR3G (Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))
- 别名
- POLR3G (POLR3G 产品)
- 别名
- 2310047G20Rik antibody, AV275904 antibody, RPC32 antibody, RPC7 antibody, polymerase (RNA) III (DNA directed) polypeptide G antibody, RNA polymerase III subunit G antibody, Polr3g antibody, POLR3G antibody
- 背景
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Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (PubMed:20154270). May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs), induce type I interferon and NF- Kappa-B through the RIG-I pathway (PubMed:19609254, PubMed:19631370).
Gene: POLR3G
- 分子量
- 26 kDa
- 基因ID
- 10622
- UniProt
- O15318
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